14 CLINICAL STUDIES

This medication is not used in children for this condition. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Common sildenafil side effects are headache, indigestion, a stuffy nose, facial flushing, suddenly feeling hot, blurred or colour-tinged vision, nausea, and dizziness. If you do happen to experience these side effects, they should only be mild and shouldn’t last long after you stop taking sildenafil. Always talk to a clinician before taking sildenafil to ensure it’s safe for you to take and won’t interact with any medication you’re taking. If you are prescribed sildenafil tablets, read the Patient Information Leaflet provided with it thoroughly before taking the medication. Medical Scientist, License for Doctor of Medicine (The Swedish National Board of Health and Welfare).

How does sildenafil work (mechanism of action)?

Sildenafil is a treatment for erectile dysfunction. It works by increasing blood flow to your penis. The brand name for this medication is Viagra®. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. NOTE: This medicine is only for you. Do not share this medicine with others. Do not take this medication with any of the following: Nitrates, such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin This medication may also interact with the following: Other medications may affect the way this medication works.

Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.

Society and culture

The good news is that treating headaches as a result of taking sildenafil can often simply be a case of altering the dose that you are taking. A study from 2000 showed that there was a significant difference between the likelihood of experiencing side effects in higher doses compared to lower doses. If you’re on 100mg or 50mg and feel you would benefit from lowering your dose, don’t hesitate to reach out to our clinical team who can advise you on how best to proceed. Other potential common side effects (which may affect up to 1 in 10 people) include: If you are prescribed sildenafil tablets, a full list of sildenafil side effects will be provided in the Patient Information Leaflet (PIL) that comes with your medication. You should read this before taking sildenafil for the first time to help you take it safely.

Marketing and sales

Sildenafil tablets should not be taken if you are allergic to sildenafil or any of the other ingredients used to make them. A list of these ingredients is also included in the PIL. A recent large-scale analysis of 16 different clinical trials showed that sildenafil and tadalafil have similar efficacy and safety profiles, meaning they are just about as safe and effective as each other. If you’re weighing your options up and don’t know which of these ED treatments to choose, you can rest assured knowing that they are both safe for most men to take. There are some medications that can interact with sildenafil if you take them both at the same time.

Erectile dysfunction

It’s important to talk to a clinician before taking sildenafil to make sure that it’s safe for you to take and won’t interact with any medications you’re taking. You should not take sildenafil if you are: Taking medicines called nitrates (which are often given for relief of angina pectoris [or “chest pain”]). Combining these may lead to a dangerous fall in blood pressure. Taking medicines called nitrates (which are often given for relief of angina pectoris [or “chest pain”]). Using any of the medicines known as nitric oxide donors such as amyl nitrite (“poppers”). This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use.

Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine. Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

• Some users experience visual disturbances, such as blue-tinged vision, after taking sildenafil.
• This side effect is generally rare and temporary.
• Report any persistent or severe visual changes to a healthcare provider.

Tell your care team right away if you have any change in your eyesight or hearing. This medication may affect your coordination, reaction time, or judgment.

The numan take

We do not endorse non-Cleveland Clinic products or services. SILDENAFIL (sil DEN a fil) treats erectile dysfunction (ED). It works by increasing blood flow to the penis, which helps to maintain an erection. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. They need to know if you have any of these conditions: History of blood diseases, such as sickle cell anemia or leukemia Stomach ulcers, other stomach or intestine problems An unusual or allergic reaction to sildenafil, other medications, foods, dyes, or preservatives Take this medication by mouth with a glass of water. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

6.2 Postmarketing Experience

The more blood that flows into the penis, the harder it becomes. Think of it like a balloon, if that helps. By increasing the flow of blood to the penis, sildenafil can generate stronger erections in men with erectile dysfunction. Other PDE5 inhibitors work in a similar way, which is why they're so effective at treating ED. Taking sildenafil - or any other PDE5 inhibitor - won’t give you an instant erection.

Missed Dose

It usually takes an hour to kick in and will stimulate an erection only when you’re sexually aroused. This is helpful because this gives you more control over your erections and allows you to get an erection when the time’s right. After all, it would be pretty inconvenient to take a tablet that gives you an instant erection against your will. Sildenafil’s effects last for around four hours. But fret not, this doesn’t mean you’ll have a constant erection for hours on end.

How is sildenafil supplied (dosage forms)?

It just means that you’ll be able to get an erection when you need one during the four hours that it’s active in your body. Sildenafil has been used as an erectile dysfunction treatment for over 20 years and is clinically proven to be safe and effective for most men. Like any medication, though, sildenafil can sometimes cause side effects. Not everybody gets them and most of the side effects reported with sildenafil are fairly mild and don’t last long. The most common side effect of sildenafil is headache, affecting about 25% of people who are prescribed it. Contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage. If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medication, you should refrain from further activity and call your care team as soon as possible.

• Sildenafil 100mg can be effective for men aged 40-70 but may vary based on health.
• Regular check-ups are recommended to assess efficacy and safety.
• Adjustments to dosage should only be made under medical advice.

Using this medication does not protect you or your partner against HIV or other sexually transmitted infections (STIs). Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects.

Why is generic medication often cheaper than the brand-name equivalent?

Follow the directions on the prescription label. The dose is usually taken 1 hour before sexual activity. You should not take the dose more than once per day. Do not take your medication more often than directed. Talk to your care team about the use of this medication in children. Keep out of reach of children and pets.

My “little blue pill” isn’t blue, it’s white. Is this normal?

Taking these at the same time as sildenafil may also lead to a dangerous fall in blood pressure. As with any medicine, it’s always best to read the Patient Information Leaflet (PIL) that comes with your sildenafil tablets before taking them. We at Numan also provide a link to a Safety Information Page for easy reference, so you can check important safety information with greater convenience. Certain conditions can make it unsafe to take sildenafil. You should not take sildenafil if you have: Recently had a stroke or a heart attack, or if you have low blood pressure.

Recreational use

Recently had a stroke or a heart attack, or if you have low blood pressure. Certain rare inherited eye diseases (such as retinitis pigmentosa). Ever had loss of vision due to non-arteritic anterior ischaemic optic neuropathy (NAION). If you have (or have ever had) any of these conditions, PDE5 inhibitors such as sildenafil are unlikely to be suitable for you. If this is the case, other erectile dysfunction treatments may prove to be more appropriate.

What should I tell my healthcare provider before taking sildenafil?

This is not an exhaustive list of sildenafil 60mg conditions that make sildenafil unsafe to take. It’s highly recommended that you consult a clinician before taking sildenafil tablets so that you know if they’re safe for you to take. Sildenafil is a generally safe and effective treatment for erectile dysfunction. Like most medicines, it may cause side effects in some people, however, not everyone gets them. Many clinical trials spanning over 20 years have found it to be safe for most men to take. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).