Drug Interactions with Vardenafil You Must Know

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Use this medicine exactly as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered.

Study design

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential vardenafil for erectile dysfunction price significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended.

Some side effects can be serious. If you experience any of the following symptoms , call your doctor immediately:

Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. If you use too much, the chance of having unwanted effects is increased.

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This medicine should come with a patient information leaflet. Ask your doctor or pharmacist if you have any questions.

  • Vardenafil can interact with nitrates causing dangerous drops in blood pressure.
  • Inform your doctor about all medications before use.
  • Avoid alcohol while taking Vardenafil to reduce side effects.

You may take this medicine with or without food. This medicine best pill for ed usually begins to work within 60 minutes after taking it and stimulation of the penis is required.

What special precautions should I follow?

Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, avanafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, avanafil will not work to cause an erection. This medicine is available only with your doctor's prescription.

Is Vardenafil Available as a Brand Medication?

This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Are you currently using Vardenafil (Levitra, Staxyn)?

Vardenafil is not indicated for use in children. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of vardenafil in the elderly. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. If you have any questions about the use of vardenafil, talk to your doctor.

  • Vardenafil is often prescribed after other ED medications.
  • It is available by prescription only.
  • Always follow your healthcare provider’s instructions.

If you are using the disintegrating tablet, make sure your hands are dry before you handle the tablet.

  • Do not use Vardenafil if you have a severe heart condition.
  • It is not recommended for individuals with certain eye disorders.
  • Use caution if you have kidney or liver issues.

Do not open the blister pack until you are ready to take the tablet. Peel back the foil and take the tablet out. Do not push the tablet through the foil. Place the tablet on your tongue and allow it to melt. Use only the brand of this medicine that your doctor prescribed.

  • Storage should be at room temperature away from moisture.
  • Keep Vardenafil out of reach of children and pets.
  • Check expiration date before use.

Different brands may not work the same way. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. The dose of this medicine will be different for different patients.

References (30)

Keep vardenafil hydrochloride tabletsand all medicines out of the reach of children. Applies to the following strengths: 2.5 mg; 5 mg; 10 mg; 20 mg Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability. Maximum dose: 20 mg once a day Initial dose: 5 mg orally once a day Sexual stimulation is required for a response to treatment. A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.

Viagra™ Efficacy

Patients taking alpha-blockers should not initiate vardenafil therapy with the orally disintegrating tablet. Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity Comments: Sexual stimulation is required for a response to treatment. CrCl: 30 to 80 mL/min: No adjustment recommended. Comment: The orally disintegrating tablet (brand Staxyn) can be used in patients with mild, moderate or severe renal impairment. Mild hepatic dysfunction (Child-Pugh A): No adjustment recommended.

BJU Int

Moderate hepatic dysfunction (Child-Pugh B): 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity. The maximum dose should not exceed 10 mg. Severe hepatic dysfunction (Child-Pugh C): Use should be avoided. Comment: The orally disintegrating tablets should not be used in patients with moderate (Child-Pugh B) or severe (Child-Pugh C) hepatic dysfunction. If taking potent or moderate inhibitors of CYP450 3A4, the dose should be adjusted as follows: Ritonavir: No more than 2.5 mg in a 72-hour period Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: No more than 2.5 mg in a 24-hour period Ketoconazole 200 mg daily, itraconazole 200 mg daily, erythromycin: No more than 5 mg in a 24-hour period Safety and efficacy have not been established in patients younger than 18 years. Follow your doctor's orders or the directions on the label.

Cialis (Tadalafil)

This vidalista 20mg uk drug is not indicated for use in pediatric patients. This drug can be taken with or without food. The 10 mg orally disintegrating tablet (ODT) provides higher systemic exposure and is not interchangeable with the 10 mg film-coated tablets. The ODT tablet should be taken without liquid and immediately upon removal from the blister. Patients who require a lower or higher dose than 10 mg should be prescribed the film-coated tablets.

When to Seek Medical Attention

Patients treated with alpha-blockers, who have previously used vardenafil film-coated tablets, may be switched to ODT tablets at the advice of their healthcare provider. Patients should stop use of PDE5 inhibitors, including this drug, and seek medical attention in the event of sudden loss of vision in one or both eyes, and decrease or loss of hearing. Symptoms related to postural hypotension may occur, appropriate countermeasures are recommended. Contact the prescribing physician if other antihypertensive drugs or new medications that may interact with this drug are prescribed by another healthcare provider. Patients should contact their healthcare provider for dose modification if they are not satisfied with the quality of their sexual performance with this drug, or in the case of an unwanted side effect.

Can I buy Levitra over the counter?

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Vardenafil is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine.

PRODUCT INFORMATION

It is not known if the medicine is safe for use in these patients. Fructose intolerance—The Staxyn® disintegrating tablet contains sorbitol, which can make this condition worse. QT prolongation (rare heart condition), or history of—Use with caution. The effects may be increased because of slower removal of the medicine from the body. Phenylketonuria (PKU)—The Staxyn® disintegrating tablet contains aspartame, which can make this condition worse. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Can You Overdose on Vardenafil?

Using alcohol or tobacco with certain medicines may also cause interactions to occur. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormally shaped penis, including a curved penis and birth defects or Crowded disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high fats in the blood) or Multiple myeloma (cancer of the blood) or Non-arteritic anterior ischemic optic neuropathy (NAION; serious eye condition), history of or Smoking—May increase the chance for a serious side effect in the eye called NAION. Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke, history of—Should not be used in patients with these conditions. Stomach ulcers—Chance of problems occurring may be increased. For treatment of erectile dysfunction:For oral dosage form (disintegrating tablets):Adults—10 milligrams (mg) as a single dose, no more than once per day, approximately 1 hour before sexual activity.Children—Use is not recommended.For oral dosage form (tablets):Adults 65 years and older—5 milligrams (mg) as a single dose, no more than once per day, approximately 1 hour before sexual activity.

Interaction Partner Effect on Vardenafil Notes
CYP3A4 Inhibitors Increased Vardenafil plasma levels Use with caution, dose adjustment needed
Alpha-blockers Risk of hypotension Start with low doses, monitor closely
Grapefruit Juice Increases drug levels Avoid or limit consumption
Other PDE5 inhibitors Additive effects, risk of adverse events Generally not recommended to combine